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If symptoms of tiredness do not improve after 68 weeks of appropriate treatment, patients should contact their GP, as this may indicate an alternative or additional cause requiring investigation
The treatment might be different
Consequence 2: Nicotinamide salvage interference
Tesamorelin, a synthetic analogue of the growth hormone-releasing hormone (GHRH), appears to act by specifically stimulating the production and release of endogenous growth hormone (GH) due to its potential binding affinity for GHRH receptors
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